PUBLICATIONS

Megraw M, Pereira F, Jensen ST, Ohler U, Hatzigeorgiou AG. A transcription factor affinity based code for mammalian transcription initiation.
Genome Research 2009 Jan 13. [Epub ahead of print]

Papadopoulos GL, Reczko M, Simossis VA, Sethupathy P, Hatzigeorgiou AG. The database of experimentally supported targets: a functional update of TarBase.
Nucleic Acids Res. 2009 Jan;37(Database issue):D155-8. Epub 2008 Oct 27.

Y. Kawahara, M. Megraw, E. Kreider, H. Iizasa, L. Valente, A. G. Hatzigeorgiou, K. Nishikura. Frequency and Fate of microRNA Editing in Human Brain. NAR 2008 Sep;36(16):5270-80.

L. Zhang*, S. Volinia, T. Bonome, G.A. Calin, J. Greshock, N. Yang , C. Liu, A. Giannakakis, P. Alexiou, K. Hasegawa, C. N. Johnstone, M. S. Megraw, S. Adams, H. Lassus, J. Huang, S. Kaur, S. Liang, P. Sethupathy, A. Leminen, V.A. Simossis, R. Sandaltzopoulos, Y. Naomoto, D. Katsaros,  P.A. Gimotty, A. DeMichele, Q. Huang, R. Bützow,  A.K. Rustgi, B.L. Weber, M.J. Birrer, A.G. Hatzigeorgiou*, C.M. Croce* and G. Coukos* (2008) Genomic and Epigenetic Alterations Deregulate microRNA Expression in Human Epithelial Ovarian Cancer, PNAS, (May 13;105(19):7004-9. Epub 2008 May 5)(*co-corresponding author).

M. Megraw, P. Sethupathy, B. Corda, A.G. Hatzigeorgiou (2007). miRGen: A database for the study of animal microRNA genomic organization and function. Nucleic Acids Research,  Jan;35:D149-55.

Y. Kawahara, B. Zinshteyn, P.Sethupathy, H. Iizasa, A.G. Hatzigeorgiou, K. Nishikura (2007) Dictation of silencing targets by adenosine-to-inosine editing of microRNAs. Science, Feb 23;315(5815):1137-40.

P. Sethupathy, C. Borel, M. Gagnebin, G.R. Grant, Artemis G. Hatzigeorgiou, S.E. Antonarakis  Human mir-155 on chromosome 21 differentially interacts with its polymorphic targets in the AGTR1 3'UTR- a mechanism for functional SNPs related to phenotypes. American Journal of Human Genetics, 2007 Aug;81(2):405-13. Epub 2007 Jul 12 (corresponding author).

A. Bernal, K. Crammer, A.G. Hatzigeorgiou, F. Pereira (2007) Global Discriminative Learning for Higher-Accuracy Computational Gene Prediction. PLoS Comput Biol., Mar 16;3(3):e54.

P. Sethupathy, B. Corda and A.G. Hatzigeorgiou (2006) TarBase: A comprehensive database of experimentally supported animal microRNA targets. RNA, 12: 192-197.

L. Zhang. J. Huang, N. Yang, M. Megraw, S. Liang, T. Naylor, A. Bachetti, A. Giannakakis, G. Yao, S. Liang, A. Medina, D. Katsaros, A. Hatzigeorgiou, P. Gimotty, B. Weber, G. Coukos (2006) MicroRNAs and their associate genes exhibit high frequency genomic alteration in human epithelial cancers PNAS, USA 13;103(24):9136-41.

M. Megraw, V. Baev, V. Rusinov, S. Jensen, K. Kalantidis, A. G. Hatzigeorgiou. (2006) MicroRNA Promoter Element Discovery in Arabidopsis. RNA, 12: 1612:1619.

P. Sethupathy, J. Hirel,, A. G. Hatzigeorgiou (2006) A comparative analysis of mammalian microRNA target prediction programs. Nature Methods, 3(11):881-6.

W. Kang, R. Mukerjee, J. J. Gartner, A. G. Hatzigeorgiou, R. M. Sandri-Goldin, N. W. Fraser (2006) Characterization of the Spliced Exon Product of Herpes Simplex Type-1 Latency Associated Transcript in Productively Infected Cell. Virology, Dec 5-20;356(1-2):106-14.

Kiriakidou M., Nelson P.T., Kouranov A., Fitziev P., Bouyioukos C., Mourelatos Z. and A. Hatzigeorgiou (2004) A combined computational-experimental approach predicts human microRNA targets.Genes & Development, 18(10):1165-78.

H. Miller … A.G. Hatzigeorgiou…. International Chicken Genome Sequencing Consortium (2004) Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.Nature, 432(7018).

P.T. Nelson, AG. Hatzigeorgiou, Z. Mourelatos (2003) miRNP:miRNA association in polyribosomes, in a human neuronal cell line. RNA, 10(3):387-94.

M. Reczko, A.G. Hatzigeorgiou (2003) Prediction of the subcellular localization of eukaryotic proteins using sequence signals and composition. Proteomics,4(6)¨1591-6.

A.G. Hatzigeorgiou (2002). Translation initiation site prediction in human cDNAs with high accuracy. Bioinformatics, Vol. 17, pp. 913-919.

A.G. Hatzigeorgiou, P. Vizief, M Reczko (2001) DIANA-EST: A statistical analysis. Bioinformatics, Vol. 17, pp. 913-919.

S. Hannenhalli, W. Hayes, A. G. Hatzigeorgiou and J. W. Fickett (1999) Bacterial start site prediction. Nucl. Acid. Res., 27:3577-3582.

J.W. Fickett and A.G. Hatzigeorgiou (1997) Eukaryotic Promoter Recognition. Genome Research, 7:861-878.

J. Bolz, K. Zerfass, D. Spitkovsky, H.-J. Delius, B.Vogt, M. Eilers, A. Hatzigeorgiou and P. Jansen-Durr (1996) Cell cycle regulation of the murine Cylin E gene depends on an E2F binding cite in the promoter. Mol. Cell. Biol., 16:3401-3409.

 P. Bucher, J.W. Fickett and A. Hatzigeorgiou (1996) Computational analysis of transcriptional regulatory elements: a field in flux. Comp. Appl. In Biosci., 12:361-362.

M. Reczko, A. Hatzigeorgiou, N. Mache, A. Zell and S. Suhai (1995) A Parallel Neural Network Simulator on the Connection Machine CM-5. Comp. Appl. in Biosci.11:309-315.